{"id":2203,"date":"2019-07-08T03:05:25","date_gmt":"2019-07-07T20:05:25","guid":{"rendered":"https:\/\/kt-biotech.com\/san-pham\/acculite-h-pylori-genotyping-kit\/"},"modified":"2024-05-16T16:55:35","modified_gmt":"2024-05-16T09:55:35","slug":"acculite-h-pylori-genotyping-kit","status":"publish","type":"product","link":"https:\/\/kt-biotech.com\/en\/san-pham\/acculite-h-pylori-genotyping-kit\/","title":{"rendered":"AccuLite H.Pylori Genotyping Kit (RUO)"},"content":{"rendered":"

 <\/p>\n\n\n\n\n\n\n\n
AccuLite H.Pylori Genotyping Kit (RUO)<\/th>\n<\/tr>\n
Package<\/span><\/span><\/strong><\/td>\n50 tests\/kit<\/td>\n<\/tr>\n
Target<\/span><\/span><\/strong><\/td>\nHelicobacter pylori (H. pylori) <\/em>DNA<\/td>\n<\/tr>\n
Methods\/ Technology<\/span><\/span><\/strong><\/td>\nReal\u2013time PCR<\/td>\n<\/tr>\n
Sample Matrix\/Sample type<\/strong><\/span><\/span><\/td>\nGastric biopsy<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n

Introduction<\/strong><\/h1>\n

Helicobacter pylori<\/em> (H. pylori<\/em>) is a type of bacteria that can reside in the stomach lining, causing many dangerous digestive diseases, including:<\/p>\n

Peptic ulcer disease:<\/strong> H. pylori<\/em> is the main cause of peptic ulcer disease, leading to symptoms such as heartburn, indigestion, abdominal pain, nausea and vomiting.
\nStomach cancer:<\/strong> H. pylori<\/em> infection is a high risk factor for stomach cancer, one of the most common cancers in the world.
\nChronic gastritis:<\/strong> H. pylori<\/em> can cause chronic gastritis, leading to symptoms such as abdominal pain, bloating, indigestion and diarrhea.<\/p>\n

AccuPid H. pylori<\/em> Genotyping Kit<\/strong> uses real-time PCR (qPCR) technique that allows identification of the bacterial-specific cagA<\/em>, vacA s1\/s2<\/em> and m1\/m2<\/em> gene regions of H. pylori<\/em> in samples quickly and accurately. High accuracy and sensitivity, while minimizing the risk of foreign contamination compared to other PCR techniques.<\/p>\n

Benefits<\/strong><\/h1>\n

Accurate diagnosis:<\/strong> Accurately detect the H. pylori strain that causes the disease, helping to direct effective treatment.
\nAppropriate treatment regimen:<\/strong> Determine the drug resistance of H. pylori, help choose an appropriate treatment regimen, and limit the risk of relapse.
\nReduce the risk of complications:<\/strong> Early diagnosis and effective treatment of H. pylori helps reduce the risk of dangerous complications such as stomach cancer.
\nEffective health management:<\/strong> Provides important information to effectively monitor and manage health after H. pylori treatment.<\/p>\n

Principles<\/h1>\n

The AccuLite H. pylori<\/em> strain typing test kit (RUO) uses real-time PCR (PCR) technology to amplify and detect characteristic DNA sequences associated with different H. pylori<\/em> strains. This highly sensitive technique targets the vacA<\/em> and cagA<\/em> genes, which play important roles in bacterial virulence and drug resistance mechanisms.<\/p>\n

Testing procedure<\/strong><\/h1>\n

Sample collection:<\/strong> Gastric biopsy samples are taken from the patient’s gastric mucosa during endoscopy.<\/p>\n

DNA extraction:<\/strong> DNA is extracted from the biopsy specimen using specialized methods to ensure purity and integrity.<\/p>\n

Real-time PCR amplification:<\/strong> The extracted DNA was amplified by real-time PCR using primers specific for the vacA and cagA genes.<\/p>\n

Fragment analysis:<\/strong> Amplified DNA fragments are analyzed based on their size and fluorescence signal intensity, allowing identification of the H. pylori<\/em> strain.<\/p>\n

References<\/h1>\n
    \n
  1. https:\/\/wwwnc.cdc.gov\/travel\/yellowbook\/2024\/infections-diseases\/helicobacter pylori#:~:text=Although%20usually%20asymptomatic%2C%20H.,the%20World%20Health%20Organization%2C%20H.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

      AccuLite H.Pylori Genotyping Kit (RUO) Package 50 tests\/kit Target Helicobacter pylori (H. pylori) DNA Methods\/ Technology Real\u2013time PCR Sample Matrix\/Sample type Gastric biopsy   Introduction Helicobacter pylori (H. pylori) is a type of bacteria that can reside in the stomach lining, causing many dangerous digestive diseases, including: Peptic ulcer disease: H. pylori is the […]<\/p>\n","protected":false},"featured_media":1423,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"product_brand":[],"product_cat":[156],"product_tag":[],"class_list":{"0":"post-2203","1":"product","2":"type-product","3":"status-publish","4":"has-post-thumbnail","6":"product_cat-detection-of-human-pathogens","8":"first","9":"instock","10":"shipping-taxable","11":"product-type-simple"},"_links":{"self":[{"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/product\/2203","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/product"}],"about":[{"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/types\/product"}],"replies":[{"embeddable":true,"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/comments?post=2203"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/media\/1423"}],"wp:attachment":[{"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/media?parent=2203"}],"wp:term":[{"taxonomy":"product_brand","embeddable":true,"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/product_brand?post=2203"},{"taxonomy":"product_cat","embeddable":true,"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/product_cat?post=2203"},{"taxonomy":"product_tag","embeddable":true,"href":"https:\/\/kt-biotech.com\/en\/wp-json\/wp\/v2\/product_tag?post=2203"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}