Research

Here are some research projects that have been conducted by Khoa Thuong Biotechnology Co., Ltd:

  • Ministry – level project, HCMc National University.  “Research on application of molecular biology in diagnostic of Dengue disease, Hepatitis B, Hepatitis C, Japanese encephaliti and Human papillomavirus infection”, 2001 – 2003.
  • City project. “Developing procedure for detecting and genotyping of  HPV (Human papillomavirus)”, 2003.
  • City project. “Bacterial meningitis: rapid detection of disease causing bacterials in cerebrospical fluid using PCR and indentification of antibiotic resistance strains”, 2004.
  • City project. “Research on DNA array used for detecting meningitis pathogens”, 2003 – 2004.
  • City project. “Developing a HCV quantification procedure using Real-time RT-PCR for research and treatment”, 2004 – 2005.
  • City project. “Application of Real time RT-PCR in HCV quantification in Hepatitis C patients”, 2004 – 2006.
  • City project. “Study on different types of HPV (Human Papillomavirus) infected status of women in Ho Chi Minh city using molecular biology”. Lead by Hung Vuong hospital, 2004 – 2006.
  • Ministry – level project. “Development of CMV (Cytomegalovirus) detection procedure using PCR and Real-time PCR, CMV quantifying for research and clinical diagnostic”, 2005 – 2006.
  • City project. “Detection of basal core promoter mutation and lamivudine resistent gene mutations in HBV using PCR-RFLP” (2006 – 2007).
  • Ministry-level project, research project of Ho Chi Minh City National University “Establishment of a Real-time PCR protocol for quantifying Hepatitis B virus (HBV) in patient blood samples” (2006-2007).
  • City project. “Development and improvement of molecular diagnostic kit for HBV, HCV, HPV”, 2006 – 2008.
  • Ministry – level project, HCMc National University. “Development of monoclonal antibodies for E6 protein of HPV 18 (Human Papillomavirus)”, 2007 – 2009.
  • Nguyen Tuan Anh, Huynh Minh Tuan, Nguyen Van Vinh Chau, Ho Huynh Thuy Duong. “Abstract development of an EvaGreen Real‐time PCR protocol for the detection of several blaOXA genes in Acinetobacter baumannii”. “Y Hoc Thanh Pho”, Volume 18, No 5, 2014.
  • Tran Thien Trung, Nguyen Tuan Anh, Tran Thien Khiem, Quach Huu Loc, Tran Anh Minh, Tran Ai Anh, Nguyen Thi Minh Tam, Ho Huynh Thuy Duong. “Preliminary study of Clarithromycin and Levofloxacin resistant mutations of H. pylori by gene sequencing”. “Tap chi Khoa hoc Tieu hoa Viet Nam”, Vol. IX, No 37, 2014.
  • Tran Thien Trung, Nguyen Tuan Anh, Quach Huu Loc, Tran Thien Khiem, Tran Anh Minh, Nguyen Ngoc Minh, Tran Ai Anh, Nguyen Thi Minh Tam, Ho Huynh Thuy Duong. “Comparative study of the value of Multiplex PCR versus CLO-test and serology test in the diagnosis of H. pylori infection”.  Y Hoc Thanh Pho” Supplement of Vol. 17, No 4, 2013.
  • Tran Thien Trung, Nguyen Tuan Anh, Quach Huu Loc, Tran Thien Khiem, Tran Anh Minh, Tran Ai Anh, Nguyen Thi Minh Tam, Ho Huynh Thuy Duong. “CaqA status and vacA genotypes of Helicobacter pylori in patients with gastritis by multiplex PCR”. “Y Hoc Thanh Pho” Supplement of Vol. 17 – No 4, 2013.
  • National science and technology project, “Appication of molecular biology in breeding aquaculture species that have high economy value”. Code KC-04-01 (2002 – 2004), leaded by Research insitute for aquaculture no 1.
  • Khoa Thuong biotech Co. Ltd.. “Research on genetic diversity of White Spot Syndrome Virus (WSSV) and Yellowhead Virus (YHV) using molecular biology”.
  • Research cooperation agreement on “Appraisal of GMO detection Kit in food sample using molecular biology” with QUALITY ASSURANCE AND TESTING CENTER 3 (QUATEST 3) (2013-2014), Khoa Thuong Biotechnology Co., Ltd develops the following kit lines:

– AccuPid CaMV 35S Promoter Detection Kit;
– AccuPid NOS Terminator Detection Kit;
– AccuPid Maize zSSIIb Detection Kit;
– Accupid Soybean Lectin Detection Kit.
Quality Assurance and Testing Center 3 (QUATEST 3) conducts an evaluation of various kits and provides results in written format.

  • Nguyen Thi My Linh, Ta Dang Khoa, Ho Huynh Thuy Duong. “Detection of animal traces in vegetarian food using PCR and Realtime PCR”, Vietnam Analytical Sciences Society, 2018.

Our products are highly prized by our customers. Many of them used our kits in their research. Such as:

  • “Determination of HPV (Human Papillomavirus) prevalence in women in Ho Chi Minh city using molecular biology“ (2004 – 2006), HCMc Department of Science and Technology, leaded by Assoc Prof. PhD. Vu Thi Nhung.
  • “Application of Real-time RT-PCR in quantification of HCV (Hepatitis C virus) in patients being treated for HCV” (2004-2006), HCMc Department of Science and Technology, leaded by Dr. Pham Hoang Phiet.
  • “Preliminary study of Clarithromycin and Levofloxacin resistant mutations of H. pylori by gene sequencing” (2014), Center for Molecular Biomedicine, University Medical Center HCMC – Branch 2.
  • “Development of five diagnostic kit for Ventilator Associated Pneumonia (VAP) pathogens, using real-time PCR” (2019), in cooperation with Thanh Nhan hospital.
  • Nguyen Tuan Anh, Nguyen Van Vinh Chau, Ho Huynh Thuy Duong. “Overexpression of OXA β-lactamases in carbapenem resistant Acinetobacter baumannii strains isolated in Southern Vietnam, 2018.
  • Nguyen Tuan Anh, Tran Vu Thieu Nga, Huynh Minh Tuan, Nguyen Si Tuan, Dao Minh Y, Nguyen Van Vinh Chau, Stephen Baker, Ho Huynh Thuy Duong, “Molecular epidemiology and antimicrobial resistance phenotypes of Acinetobacter baumannii isolated from patient in three hospitals in southern Vietnam”, Journal of Medical Microbiology, volume 66, issue 1, 2017.
  • Nguyen Tuan Anh, Huynh Minh Tuan, Nguyen Kim Huyen, Nguyen Vu Hoang Yen, Trinh Thi Thoa, Huynh Kim Ngan, Vo Thi Tuyet Nga, Nguyen Van Vinh Chau, Ho Huynh Thuy Duong, “Development of TaqMan realtime PCR procedure to detect blaOXA genes in Acinetobacter baumannii”, journal “Khoa Hoc Tre”, volume 2(1), 2016.
  • Nguyen Tuan Anh, Tran Vu Thieu Nga, Huynh Minh Tuan, Nguyen Si Tuan, Dao Minh Y, Nguyen Van Vinh Chau, Stephen Baker, Ho Huynh Thuy Duong, “Molecular epidemiology and antimicrobial resistance phenotypes of Acinetobacter baumannii isolated from patient in three hospitals in southern Vietnam”, Journal of Medical Microbiology, volume 66, issue 1, 2017.